Understanding OUD: The Medications
Understanding the intricacies of methadone treatment delivery, including its administration through observed dosing at licensed Opioid Treatment Programs (OTPs) and Narcotic Treatment Programs (NTPs), the requirements for federal and state regulations, and the eligibility criteria for take-home doses, is crucial for healthcare providers and policymakers alike.
This knowledge is vital as it ensures that healthcare providers are equipped with the necessary information to deliver effective methadone treatment for opioid use disorder (OUD) and manage patient care within the framework of regulatory requirements. Additionally, policymakers can use this understanding to advocate for improved access to methadone treatment programs and to implement policies that support the expansion of treatment options for individuals struggling with OUD. Ultimately, by being informed about the intricacies of methadone treatment delivery, stakeholders can work collaboratively to enhance the quality and accessibility of care for individuals affected by OUD.
About Methadone
• Methadone, the full opioid agonist, can only be administered at licensed treatment programs, such as methadone clinics, due to its potential risk of respiratory depression.
• Methadone has a very long half-life, so there is a need to start low and go slow.
• Methadone prescription follows the 3-day rule and provides stability and structure.
• The typical effective dose range is 80-120 mg
Please listen to the following audio file for more information.
About Buprenorphine
Buprenorphine is available through licensed treatment programs or via a physician's office.
Buprenorphine comes in various dosage forms, including sublingual tablets, monthly depot injections, subdermal implants, and a mono-product (Subutex) used only during pregnancy.
Patients need to be in withdrawal to start treatment.
Buprenorphine carries a very low risk of overdose.
Please listen to the following audio file for more information.
About Naltrexone
• Naltrexone, an opioid antagonist blocks the effects of opioids.
• The requirement for patients to be entirely opioid-free before Naltrexone administration can sometimes hinder access to care.
• This issue can be circumvented for the treatment of acute pain, such as broken bones.
• Naltrexone does not protect against overdose.
Please listen to the following audio file for more information.
